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Zepbound may reduce the efficacy of birth control pills
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Among the key genes upregulated were different efflux pumps
In ferroptosis, the leading mechanism is the glutathione (GSH) depletion and inactivation of Glutathione peroxidase-4 (GPX4), which strongly shifts the oxidative balance in the cell, leading to the activation of certain signalling pathways to induce oxidative death
