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Adiponectin negatively regulates pigmentation, Wnt/-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo

These results suggest that targeting FSP1 or inhibiting its phase separation initiates ferroptotic cell death is a potential anticancer paradigm

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doi: 10.1093/toxsci/kfw012 216 SchrammR.AppelF.ReinacherM.SchfersH

To some extent, glutathione exposure alone was sufficient to induce increased expression of these genes in vitro

Research by GPS has the potential to enhance the expression of pro-apoptotic proteins, including Bax, which is a critical metabolite of the Bcl-2 protein family