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Copper peptides behave differently than most active ingredients

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1Simon A., Wegrowski Y., Bontemps Y., Maquart F.X. Expression of glycosaminoglycans and small proteoglycans in wounds: Modulation by the tripeptide-copper complexglycyl-L-histidyl-L-lysine-Cu( 2+ )J. Investig. Dermatol.2000;115:962968. doi:10.1046/j.1523-1747.2000.00166.x

However, while some studies noted increased vanin-1 activity in diabetic models, the absence of vanin-1 resulted in only mild improvements in glucose tolerance and insulin sensitivity 41

It contains approximately 70% ethylene oxide, which accounts for its hydrophilicity