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A complete list of all used antibodies and their respective dilutions is found in Supplementary Table 5

Strikingly, upregulation of the de novo ser/gly synthesis pathway has been shown to cause resistance to BRAF inhibitors in NSCLC cells [11]

High-dose IV vitamin C, however, carries real risks and should only be given under qualified medical supervision after screening for G6PD deficiency, kidney disease, and iron overload

Two key regulatory pathways (p16-CDK4-RB and ARF-MDM2-p53 pathway) are involved in controlling cells duplication activities from unrestrained progression of cell cycles, whereby the principal proteins involved in these distinct pathways are retinoblastoma tumor suppressor protein (RB) and p53 tumor suppressor protein (Fig

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(9) Acetate is incorporated into the Krebs cycle as acetyl coenzyme A (acetyl CoA), but if it is not transferred to the cycle, its accumulation may result in the production of ketone bodies leading to ketonuria and ketonemia
