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Description
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Neurotoxicity is apparently dose-dependent (frequent for 250350 mg/m 2 , almost certain if dosage exceeds 500600 mg/m 2 ) [102], although cases of early onset have been described, particularly in patients with neuropathy risk factors [103]

Curr Heart Fail Rep

In the myocardium affected by various pathological factors, the inhibition of GSH and GPX4 is ubiquitous
Additionally, NAC infusion also resulted in increased total and reduced NAC levels in skeletal muscle at 45 minutes of exercise and at fatigue

doi: 10.1002/ajmg.a.34114
