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doi: 10.1002/bjs.1800540212

The titration schedule is a maximum framework, not a mandatory escalation

After injection (monitoring phase) Immediately: Apply cold compress for 10 to 15 minutes First hour: Monitor for any unusual symptoms beyond the injection site First 24 hours: Repeat cold compress every 2 to 3 hours if a reaction develops First 48 hours: Apply hydrocortisone 1% twice daily if redness or itching persists Day 3 to 7: Switch to warm compress if swelling or lumps remain

Results can vary

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