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doi: 10.1002/cncr.24929

He was found to have conjunctival hyperpigmentation along with striking pigmentary changes in the macula of both eyes (Figure 4)

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Peripheral Effects While the primary mechanism is central, PT-141 also has peripheral actions: Genital blood flow: Some increase in genital vasocongestion has been measured, likely secondary to central nervous system activation Blood pressure: Transient increases in blood pressure occur after injection (a significant clinical consideration) Pigmentation: Mild tanning effect possible, though less pronounced than Melanotan II 3

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Synthesis and characterization of a 68Ga-labeled N-(2-diethylaminoethyl)benzamide derivative as potential PET Probe for malignant melanoma