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For example, oxidative stress exacerbates lung inflammation in respiratory viral infections such as severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and influenza A virus infections ( Severe SARS-CoV-2 infection is characterized by cytokine storm, coagulopathy, and endothelial inflammation driven by excessive immune activation

& De Iuliis, G

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however, the 500 mg twice daily dose was significantly more efficacious than the 250 mg twice daily dose

10.3390/jcm5020023 117

Notably, patients with high ENO2 expression had poorer OS and RFS compared to those with low ENO2 expression (Fig