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Within the ER, newly synthesised proteins are oxidised by PDI, which in turn are again re-oxidised by ER oxidoreductase 1 (ERO1) in a reaction that generates H 2 O 2 72 , reviewed by 76

While many fungi play beneficial roles in medicine (e.g., Ganoderma lucidum , Poria cocos ), agriculture (e.g., mycorrhizal fungi enhancing plant nutrient uptake), and the food industry, a considerable number also pose serious threats to human health, agricultural productivity, and ecosystem stability

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doi: 10.1016/j.cell.2010.01.022 44 CarioEGerkenGPodolskyDK