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To address this discrepancy, we conducted extended 100 ns simulations of SpyCatcher003 wildtype, S59C, and S59C-biotin in the presence of bound SpyTag at elevated temperature (Supplementary Fig

Zhou Y, Huang J, Zeng L, Yang Q, Bai F, Mai Q, Deng K (2024) Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway

Together with the recent studies on benzene sulphonamide derivatives 8,28 , it is clear that site I presents a druggable pocket, and our high-resolution results provide a firm basis for structure-led drug discovery

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