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Nicotinamide deoxyriboside derivatives, such as nicotinamide 2-deoxyriboside and 5-methylnicotinamide 2-deoxyriboside, act as mechanism-based small molecule inhibitors of CD38 by forming stable covalent intermediates 132

B12 (hydroxocobalamin) is a prescription-only medicine in the UK and is safest given by, or under the supervision of, a trained clinician