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Targeting soluble abeta peptide with tramiprosate for the treatment of brain amyloidosis

American Journal of Physiology-Endocrinology and Metabolism, 319(4), E659E666

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P53 regulates redox balance by downregulating SLC7A11 to reduce cysteine and GSH levels, increasing ROS, and upregulating ALOX15 via SAT1 to enhance lipid peroxide production (Kang et al