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(III) Peptide targets TLR2, enhances the directivity and enrichment of oridonin within AML cells

A novel mechanism for human K2P2.1 channel gating

Additionally, previous research has demonstrated that ghrelin can enhance blood circulation in the digestive system in a sepsis model and potentially prevent the apoptosis of stomach mucosa cells by regulating apoptosis-related elements in gastric tissues, including B-cell lymphoma 2 (Bcl-2), Bcl-2-associated X (Bax), and caspase-3 proteins (112)

More importantly, co-delivery can produce synergistic effects- the combined efficacy is greater than each component alone- by synchronizing their bioavailability (89)

Approximately 20-30 hours, compared to roughly 12-15 hours for native IGF-1

doi: 10.1016/j.pnpbp.2019.109757 55 FragaD