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Like its better-known relative GHK-Cu (Glycyl-Histidyl-Lysine copper), AHK-Cu is a tripeptide three amino acids bonded in sequence with a copper(II) ion coordinated to the peptide backbone

10.5339/gcsp.2015.2 69 EnesS

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Destabilization of the metal binding site may reduce the metal affinity or binding ability of G93A SOD1, resulting in the pathological aggregation observed in mouse models and humans with this mutation

Ann N Y Acad Sci 1019:346349 Lopez-Barea J, Barcena JA, Bocanegra JA, Martinez-Galisteo E, Peinado J (1990) Structure, mechanism, functions, and regulatory properties of glutathione reductase