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EGCG, a polyphenol, has been found to increase the expression of key autophagy-related proteins, leading to improved clearance of cellular debris and damaged organelles

However, the nose-to-brain pathway is still not completely understood and there appear to be different routes for drugs to reach the brain and distribute across its parenchyma (Fig

Additionally, it exhibits anti-inflammatory effects, reducing swelling, nerve damage and pain associated with injuries

In another study, it was demonstrated that p50-NF-B is susceptible to S -glutathionylation on Cys62, thereby inhibiting DNA binding [98]

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Impact of the level of adherence to mediterranean diet on the parameters of metabolic syndrome: a systematic review and meta-analysis of observational studies