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An associated reduction in lipid accumulation, increased levels of adipocyte markers including peroxisome proliferator-activated receptor-, adiponectin, and CCAAT/enhancer binding protein-, as well as continuous expression of monocyte chemoattractant protein (pre adipocytes marker) were observed [96]

Mov Disord 38:710711 Mller T, Muhlack S (2009) Peripheral COMT inhibition prevents levodopa associated homocysteine increase

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Malignant brain tumors known as glioma or glioblastoma exploit this phenomenon by using glutamate as an energy source, especially when these tumors become more dependent on glutamate due to mutations in the gene IDH1

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Meles SK, Oertel WH, Leenders KL