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Mandic A, Hansson J, Linder S, Shoshan MC

Research shows that around 50 percent to 60 percent of ingested vitamin B12 is usually absorbed when enough intrinsic factor is present in relation to B12, but absorption decreases drastically when this ratio changes

doi: 10.1016/j.cell.2013.12.010

Furthermore, atrophy and inflammation of mucosal surfaces in the gut are documented in experimental TD (82), and high doses of thiamine have been trialed in two studies showing that thiamine reduced fatigue associated with IBD (199, 200)

[DOI] [PMC free article] [PubMed] [Google Scholar] 86.McBean G.J