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In general, more neurotropic, cyst-forming strains (e.g., Type II) establish long-term brain infections and robust neuroinflammation, which tend to produce measurable behavioral alterations

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Furthermore, Demircan et al

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Notably, glutamine, glycine, leucine, or lysine depletion does not change CD3 chain expression, suggesting that arginine plays a unique role in TCR signal transduction [235]