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Ineffective erythropoiesis leads to the formation of large, spherical erythrocytes, the lifespan of which is shortened due to their abnormal structure and lower resistance to mechanical damage and other environmental conditions

Gut Liver

Protection afforded by sickle-cell trait against subtertian malareal infection

Sarkar S, Bhui U, Kumar B et al (2024) Correlation between cognitive impairment and peripheral biomarkers - Significance of phosphorylated Tau and amyloid- in alzheimers disease: a new insight

NPY exerts potent neuroprotective effects through the inhibition of cell death, increased trophic support, the inhibition of glutamatergic excitotoxicity, and the normalization of autophagy [122]

The value of MMA rises with vitamin B12 deficiency