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In Ang II-challenged mice, the vascular media thickness, media-to-lumen ratio, and collagen deposition were reduced by 26.19%, 27.05%, and 30.40%, respectively, following intragastric administration of NMN, and elastin expression was restored by 24.38% after NMN treatment (Supplementary Fig

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Thus, providing the suitability of the both models, and damaging regimens used, these arguments ( i.e