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This kind of NP involves predominantly sensory nerves and occurs in a stocking-and-glove distribution

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doi: 10.1016/j.ejpb.2013.09.008

The CaAb-IGF-1 fusion protein had sustained cartilage binding ability and IGF-1 biological activity, promoting cartilage formation in model mice

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Although there is an unresolved dispute over the contribution of the tight junction barrier to the disease pathology, recent studies have concluded that even in the presence of a normal underlying immunity, functional abnormalities of tight junction proteins could result in these diseases