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Mechanistically, Beclin-1 binds to solute carrier family 7 member 11 (SLC7A11), a crucial part of system Xc-, inhibiting its action and subsequent ferroptosis through phosphorylating at ser90/93/96 (Song et al., 2018)

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The poor bioavailability of HTyr observed in different studies related to the low or null concentration of circulating HTyr is due to the subsequent extensive first-pass phase-I and phase-II metabolism in the gut and liver [109]

Discussion on the use of turmeric in the treatment of Bi syndrome

Gaurav Jain, Dr
