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The most representative examples of small molecular antioxidants involve vitamins C, E, and A, polyphenols of which about half are flavonoids, carotenoids, glutathione, curcumin, melatonin, and others (Niki 2016)

The impact of senescence-associated T cells on immunosenescence and age-related disorders
doi: 10.1080/095530099139449
Additionally, researchers observed a notable increase in the thickness of the epidermal layer, which might indicate an influence of elevated growth hormone levels on epidermal cell proliferation

Consequently, TNFAIP2 knockout during PD-1 therapy could significantly bolster survival rates in glioma patients (88)
Within extrahepatic tissues retinol is bound, primarily, to one of two RBPs, identified as RBP1 and RBP2
