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(2019) Open trial of vitamin B12 nasal drops in adults with myalgic encephalomyelitis/chronic fatigue syndrome: comparison of responders and non-responders
Vitamin B-12 concentrations in breast milk are low and are not associated with reported household hunger, recent animal-source food, or vitamin B-12 intake in women in rural Kenya
Severe neurological damage from prolonged deficiency can become permanent if not treated promptly which is why accurate and timely diagnosis matters more than choosing a particular supplement form

Vitamin A and/or antibiotics may also be prescribed

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For adults then, Vitamin B12 deficiency will only and always closely follow and resemble Cobalt deficiency
