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These effects are dose-dependent and typically diminish over time with continued use

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[21] In a 2003 meta-analysis of 21 clinical trials, a total of 1,204 adults with mild cognitive impairment took supplements containing 1.5 g to 3.0 g/day acetyl L-carnitine (ALCAR) or placebo for 3 to 12 months

Clin Ter 1995 Dec;146(12):769-74 [abstract] Kopke RD, Coleman JK, Liu J, Campbell KC, Riffenburgh RH

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