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These roles of ROS highlight their importance not only in normal cellular functions but also in the body's defense mechanisms, emphasizing the need for a delicate balance to prevent oxidative stress and associated diseases

Overall, although the [ 11 C]Ro15-4513 V T reflects the net effect of the availability of these different GABA-A receptors, the 20-fold greater affinity of [ 11 C]Ro15-4513 for 5-GABA A Rs and the enriched expression of 5-GABA A Rs in the hippocampus indicates the lower [ 11 C]Ro15-4513 hippocampal availability is likely to predominantly reflect lower 5-GABA A R levels

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