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To better verify whether HSP90 is a direct target of Tim-AIII, the interaction and viscosity coefficient between Tim-AIII and HSP90 were examined by a SPR assay

Ayala A, Muoz MF, Argelles S (2014) Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal

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The rationale is that the pathology leads to the elevation of pulmonary arterial pressure, which correlates inversely with lung function

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[5] showed that glutamine metabolism is inhibited at the end of anagen follicle growth, allowing progenitor cells to return to the hypoxic ecological niche, restoring the stem cell state and regenerating bulge for long-term maintenance of HFSCs