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However, when exposed to long-term disturbances, GM composition can adapt, although substantial perturbations may result in a dysbiotic state (Korach-Rechtman et al

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Moreover, H 2 S S-sulfhydates sirtuin isoform 1 (SIRT1) at Cys371, Cys374, Cys395 and Cys398, thereby enhancing its deacetylase activity and further amplifying the Nrf2-mediated antioxidant response [70]

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