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Their effect remains subject to somatostatin's inhibitory tone, keeping them within the natural feedback system
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The body therefore maintains free heme concentrations at an extremely low level that is undetectable in the plasma of healthy individuals
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doi: 10.3389/fphar.2020.578396, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Pasierski M., Szulczyk B
In addition to these effects, there is a link between increased NO production and inflammation-related disorders
