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All samples were compared to the WT vehicle-treated group
COL3A1 testing identified the Glu682Lys variant (identical pathogenic variant to family 1 and family 4), which was subsequently identified in the father (IV.1) and another daughter (V.3)
Succinate accumulation inhibits CPT1 by elevating levels of acyl-CoA dehydrogenase, suppressing FAO (Yu et al
BaekSKimJMoonBSParkSMJungDEKangSYet al
2.4 Mitochondrial dysfunction in PD Mitochondrial dysfunction is intricately linked to PD etiology and ferroptosis
