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Plasma FGF21 levels are increased in patients with hypothyroidism independently of lipid profile

This is unlike cytosolic fatty acid synthesis which is catalyzed by two enzymes, acetyl-CoA carboxylase 1 (ACC1) and fatty acid synthase (FAS)

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doi: 10.1111/j.1743-6109.2011.02519.x

A contrasting pattern was detected for the gene expression of cytochrome c oxidase subunit 4I1 (COX4I1), with stable levels in CON and a downregulation in CAR due to LPS injection

The photoperiod was set at 16L : 8D throughout the experimental period
