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Circ Cardiovasc

5 and 6

While regular physical activity confers neuroprotection through multiple pathways [109], emerging evidence indicates that sedentary behavior independently contributes to PD risk, possibly via chronic systemic inflammation and reduced cerebral perfusion [110, 111, 112, 113]

Conjugates formed between glutathione and toxic metabolites are further metabolised into cysteinyl-s-conjugates, which have long half-lives in circulation

QSM values from the occipital white matter region were considered as the reference in our study as this brain region has been reported to have the least susceptibility variation in HC and PD groups

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