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Then they were cut into 4-m thick coronal brain sections and mounted on slides

doi: 10.1186/s12964-025-02308-7 197 ZhangX

Furthermore, early-life Pb exposure has been associated with epigenetic modifications, including promoter methylation and histone acetylation changes in genes encoding glutamate transporters, potentially leading to long-term transcriptional repression [8,89,94]

Beyond classical antioxidant signaling, GSH interfaces with additional pathways, including Hippo-Yes1 associated transcriptional regulator (YAP1) signaling to regulate GPX4 and SLC7A11 expression, 159,160 mechanistic target of rapamycin kinase (mTOR) signaling to influence GPX4 protein synthesis through cysteine metabolism, 161 and NF-B signaling to restrain inflammation-associated ROS production 162

Suzuki T, Takahashi J, Yamamoto M

Antibiotic claims stem from infection triggers (fever/oxidants), not resistance