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doi: 10.1007/S11356-022-19718-6 122

Standard formulations or unstable compounds may degrade before the body uses them effectively

71 The only patients who may benefit from activated charcoal beyond 4 hours of ingestion are those who ingested extended-release APAP formulations or co-ingestion of drugs that delay gastric emptying time

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The SELECT trial (2023) further established semaglutides cardiovascular benefits, showing a 20% reduction in major adverse cardiovascular events in overweight adults with established heart disease even without diabetes