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648 Another analysis concluded that although the benefit was not consistent across all studies, those with greater calcification at study entry had the greatest likelihood of benefit

Baranovicova E, Grendar M, Kalenska D et al (2018) NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia

Ying W, Wei G, Wang D, et al

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The change induces difficulty in repairing ruptures of double-stranded DNA, increases ROS production, mitochondrial dysfunction, with concomitant oxidative stress and consequent cell apoptosis [10, 11]