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For routine mild dehydration in healthy athletes, the performance advantage of IV over oral rehydration is not conclusively established

2018;97:e13108

Sumoylation increases HIF-1 stability and its transcriptional activity

In a double-blind, randomized, placebo-controlled trial involving 40 renal transplant candidates, melatonin reduced urinary NGAL and multiple oxidative stress markers, with renal injury biomarkers, inflammatory mediators, and oxidative stress indices as study endpoints (261)

Aldehyde-modified proteins are highly immunogenic

In target tissues, such as the liver and the brain, T 4 (the most abundant circulating thyroid hormone) can be converted to T 3 by selenium-containing enzymes known as iodothyronine deiodinases (DIOs) ( Figure 1
