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Among natural permeation enhancers, terpenes such as -bisabolol that have gained attention due to their ability to interact with mucosal lipids, enhancing drug permeability without affecting tissue integrity, as demonstrated in vitro studies using porcine mucosa in small drug molecules [95]
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Cytotoxicity was determined by colony-forming capacity
Polymorphism of phase II enzymes: identification of new enzymes and polymorphic variants by database analysis
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