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A., Rasheed, R., Shahid, M., Ali, S., & Sarker, P
Alkylated proteins were incubated with either 10 g trypsin (4 h at 37C) in ABC buffer, or 10 g pepsin (1 h at 37C) with added 1% formic acid in 10% MeOH to obtain pH 2 during digestion
Weight-based dosing offers an alternative approach at approximately 0.085 mg per kilogram of body weight per week
& Pare, D
Molecules, 28 (20), Article 7165
However, the lack of regulatory approval means comprehensive safety dataincluding potential effects on sexual functionhas not been systematically collected or evaluated
