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Both are high-efficacy weight-loss agents built on dual-pathway agonism CagriSema adds amylin to GLP-1, tirzepatide adds GIP to GLP-1

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In particular, the improvement of intestinal wall integrity occurs due to the three main mechanisms: i) increased expression of TJ proteins, ii) decreased levels of pro-inflammatory molecules, and iii) increased intracellular antioxidant potential (Sandoval-Ramrez et al., 2021)

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A Protocol section 1 1 1 4 states
