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Down-regulation of T lymphocyte activation in vitro and in vivo induced by glycoinositolphospholipids from Trypanosoma cruzi

Almeida CG, Takahashi RH, Gouras GK
Kyriakoudi et al., 2021)

This may contribute to MCAS

In particular, a molar excess of thiols (from 10 up to 100-fold) over hemin leads to a shift (by 1020 nm) of the Soret peak of hemins spectrum, which is accompanied by its decline to almost disappearance
This allows homotaurine to act as an agonist of the GABAA receptor, exerting inhibitory effects on the central nervous system (CNS)