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4 Mechanism of the protective effect of PCs on diabetes mellitus 4.1 Improve the insulin resistance Insulin, an essential hormone secreted by pancreatic -cells, regulates glucose metabolism and exerts a profound influence on blood glucose levels ( Located in the cell membrane, the insulin receptor exhibits a tetrameric structure with two -chains and two -chains, serving as the primary hub for insulin action and orchestrating the insulin signaling cascade

The primers GM3F (5-AGAGTTTGATCATGGC-3) and GM4R (5-TACCTTGTTACGACTT-3) were used to amplify the 16S rRNA gene of bacterial samples

To limit the enzyme activity in Brassica, a seed-specific antisense construct of rapeseed -9 desaturase was used

Simpson JP, Di Leo R, Dhanoa PK, Allan WL, Makhmoudova A, Clark SM, Hoover GJ, Mollen RT, Shelp BJ (2008) Identification and characterization of a plastid localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification

Its specificity for the GHS-R receptor allows it to produce robust effects without broadly disrupting other hormonal pathways

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