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Through next-generation sequencing and precision genomics, our genetic screening evaluates polymorphisms in genes such as HLA-DRB1, BTNL2, ANXA11, and NOTCH4 , all of which have been strongly associated with Sarcoidosis susceptibility and progression

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Under the H 2 O 2 stress, CAUH2 cells enhance the uptaking of cuprous ions by the up-regulated expression of genes ndh2 and copA to maintain the activity of heme-dependent catalase and glutathione peroxidase, which detoxify the cells by transforming H 2 O 2 into H 2 O and O 2

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For instance, a single-center study involving 200 type 2 diabetes patients, stratified by UACR categories (normal, micro-, and macroalbuminuria), found that the combined measurement of C16, C18:1, and C3 achieved an area under the receiver operating characteristic curve (AUC) of 0.89 for early DKD diagnosis, significantly outperforming UACR (AUC = 0.76) [147,148,149,150]