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Because fasted-state absorption allows the peptide to bind NNMT enzymes without interference from competing substrates in the gut

Laboratory studies Complete blood count was measured with automatic blood count device LH 750 (Beckman Coulter, Inc., USA), and VB12 level was measured with automatic biochemistry device Advia Centaur XPT (Siemens, Berlin, Germany)

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Micro computed tomography Rats (n=12) were anaesthetized again and the mandibles were excised, separated from the surrounding tissues and cut in half in a sagittal plane between the incisors and were processed

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Targeted therapies have a potential of achieving control over the metastatic disease with limited toxicity and controlling the disease with long-term survival of patients