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Notably, miR-99a-5p, miR-379-5p, and miR-497-5p showed a loss of editing in 100%, 80%, And 87% of matched tumor samples, respectively, while miR-200b-3p exhibited increased editing in 46% of cases

4r), both of which are associated with memory T cell precursors and superior antitumor activity 18

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The result can include increased oxidative stress, inflammation, and cellular damage

ROS can activate AMP-activated protein kinase (AMPK) or inhibit protein kinase B (Zhao et al., 2017), which represses mTORC1 complex activity and enhances autophagy (Li et al., 2019