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There is some evidence that the diabetes drug metformin (Glucophage) may reduce vitamin B12 absorption when used for several years
B12 supplements should be avoided by those with known cobalt sensitivity and used with caution in people with Leber's hereditary optic neuropathy
Where relevant data were missing, attempts were made to contact corresponding authors
People who cannot digest B12 can take a supplement that is placed and absorbed under the tongue (sublingual), inhaled through the nose, or given as a shot injected into muscle
Martin Wainscott in Australia, a study deemed unusually intense in the frequency and dosage of the cobalt administered drew similar conclusions
B Complex shots may be beneficial for a range of individuals, especially those who are focused on improving energy, wellness, and metabolic support
