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Derin A, Agirdir B, Derin N, et al
Mutant IDHs, accounting for 80% of lower-grade gliomas and secondary GBM, continuously produce 2-HG

doi: 10.1038/s41582-023-00918-8, PMID: [DOI] [PubMed] [Google Scholar] 78.Jenner P, Rocha J-F, Ferreira JJ, Rascol O, Soares-da-Silva P

12 With overdoses, peak plasma concentrations are usually achieved within 4 hours

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