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The finding that maternal supplementation during pregnancy and lactation significantly increased vitamin B-12 concentrations in breast milk is novel and potentially important

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This type of cochlear synaptopathy, referred to as hidden hearing loss because the deficits can hide behind a normal audiogram 11 , is posited to trigger neural hyperactivity that underlies tinnitus 19,20,21 , potentially offering a valuable drug target for the development of novel tinnitus treatments

Also, predicted binding free energy using molecular mechanics/generalized Born surface area for each docked pose was consistent with in vitro enzyme inhibition for both mushroom and murine tyrosinases

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