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However, administration of GH and subsequent GH-mediated effects were found to be dose dependent, as high concentrations given to GH-deprived canines caused atrophy of testes and accessory organs, thinning of prostatic epithelium and a reduction in LH and testosterone levels (75)
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Haematological changes were found in rats at all doses, but mainly at the end of the study in animals exposed to 173 mg/m 3

Simple rule: start conservative, re-test in a few weeks, and adjust to your objective labs + how you feel

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Conclusively, lycopene supplementation proved valuable to combat against hyperglycemia (Duzguner et al., 2008[36])