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Since nicotinamide boosting could increase the production of oxyradicals from the ETC, we treated the hippocampal neurons with EGCG to control an oxidative redox state that causes ROS overproduction

Then we asked whether this effect was mediated by the decrease of Notch2 caused by NAC

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Journal of Biological Chemistry 291, 30533062

Required Samples of Pull Down The samples come from animal and plant tissues, cells, etc., and the amount of samples can affect the content of proteins

However, for patients with sensitive gastrointestinal tracts or severe cellular depletion, standard oral Vitamin C often falls short due to poor absorption