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Description
Leucine-rich repeat and immunoglobulin-like domain-containing protein 1 (LINGO-1), which was discovered by Biogen, 16 suppresses oligodendrocyte differentiation, axonal regeneration, and neuronal survival

You have a lot of them when your immune system is working against your tissues

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Intervertebral disc regeneration: do nutrients lead the way

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Hence, the microclots may result in decreased circulation and blockage of the microcapillaries, resulting in ischemia and therefore many symptoms of ME/CFS, as seen in Figure 9
